The American Repertory Theater stages Ionesco’s absurdist classic at the Loeb Drama Center in Harvard Square, and the occasion is a big one: Diane Paulus directs her last production in the building before the company decamps to its new Allston home. John Turturro plays Berenger, the lone holdout in a town whose citizens keep turning into rhinoceroses, alongside Paul Giamatti and Tatiana Maslany — three Emmy winners sharing one stage.

The play is a dark comedy about conformity — funny, unsettling, and pointed enough to feel like it was written last week rather than in the wake of the Second World War. Expect a fresh adaptation and a starry, sold-out-caliber run, so book tickets early. Select performances offer open captioning, ASL interpretation, and audio description.